Sustine^® 110 IM is a non-specific immobilized lipase that offers cost-efficient recyclability and works well with stereoselective hydrolysis of esters, transesterification and esterification of acids, and acylation of amines.

The biocatalytic properties of Sustine^® 110 IM are already being used in the manufacturing of known commercial active pharmaceutical ingredients (APIs), such as: 

• Molnupiravir
• Trandolapril
• Amino hydroxypiperidine derivatives
• Pimecrolimus

It is also used as a catalyst to manufacture key agro intermediates (AIs):

• S-metolachlor and S-dimethenamid – Herbicide intermediate (S)-MOIPA

Other commercial APIs/AIs that use Sustine^® 110 IM include:

• Moxifloxacin
• Posaconazole 
• S-Flurbiprofen
• Ketorolac
• Chloramphenicol
• Analogues of mevinic acid
• (S)-1-(2-furyl)ethanol
• Intermediates in the synthesis of Stagonolide E, Pyrenophorol and Decarestrictin L
• Naphthofurandion derivative 

Sustine^® 110 IM is identical to the former Novozymes product, Novozym® 435.