Name: Sustine® 140
Brand: Novozymes

Get in touch

Cookie policy

Privacy policy

Privacy policy for Novozymes’ recruiting system

Legal notice

Sitemap

Regulatory compliance

Non-financial site data

Whistleblower hotline

General terms and conditions

Helpful links

Advanced protein solutions

Food & beverages

Household care

Human health

Professional cleaning

Consumer biosolutions

Animal Health & Nutrition

Leather & textiles

Aquaculture

BioAg

Pulp & paper

Bioenergy

Carbon capture

Fine chemicals

Agricultural & industrial biosolutions

Product safety

Quality and safety

Supplier management

Awards

Novozymes Market

Control reports

About Novozymes

Facebook

LinkedIn

YouTube

Instagram

Distilling

Grain & starch

Our solutions

Powerful biotech

What are enzymes?

What are microbes?

The world's best kept secret

Media & news

Sustainability

How we work with sustainability

How we perform on sustainability

Impacting the world with biotech

How we transform food systems

How we do business

Investors

Careers

Purpose

Open positions

Career opportunities

Work for a cause, not just a company

About us

Strategy

Business model

Why choose Novozymes

Positions & policies

Leadership & ownership

Our subsidaries

Our history

Get to know us

Broad specificity

Organic solvent friendly

Works well with polyol esters

Request free sample

Sustine® 140 is a liquid lipase that works well with glycerides/polyols esters, regioselective hydrolysis and esterification.

Sustine® 140 is already being applied in a number of commercial active pharmaceutical ingredients (APIs) and their intermediates, such as: 

<ul><li>Temsirolimus </li>
</ul>

Broad specificity Organic solvent friendly Works well with polyol esters

Benefits

IMPORTANT INFORMATION 
Novozymes does not promote or support the use of enzymes as Active Pharmaceutical Ingredients (APIs) or excipients. Novozymes enzymes are industrial bulk products and are not produced according to pharmaceutical standards. Novozymes does not analyze all impurities and/or carry over in the enzyme product. If enzymes are used as process aids, it is the responsibility of the API or excipient manufacturer to assure that the enzymes are suitable for the intended use, including but not limited to evaluation of purity and absence of carry over in final API or excipient product.

Details

This product contains enzymes. While enzymes are safe to use in consumer applications, they need correct handling in working environments to ensure workers’ safety.

Indeed, repeated inhalation of enzyme dust or aerosols resulting from improper handling may induce sensitization and may cause allergic type 1 reactions in sensitized individuals.

Please follow the precautionary handling recommendations below:

<article class="align-right media media--type-image media--view-mode-ckeditor-medium"><div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img src="https://cdn.novozymes.com/sites/default/files/styles/small_proportional/public/image/2023-03/safe_handling_icon.png.webp?itok=mCNXGSFp" width="120" height="121" alt="safe handling icon" loading="lazy" class="image-style-small-proportional" /></div>
 
 </article><ul><li>Avoid breathing dust/fume/gas/mist/vapors/spray</li>
	<li>Avoid contact with eyes, skin, or clothing</li>
	<li>In case of inadequate ventilation wear respiratory protection</li>
	<li>IF INHALED: Remove person to fresh air and keep comfortable for breathing</li>
	<li>If experiencing respiratory symptoms: Call a POISON CENTER or a doctor</li>
	<li>Store in a dry place. Store in a closed container</li>
	<li>Dispose of contents/containers in accordance with local regulations</li>
</ul>For recommendations on how to safely handle the enzyme product, please visit the <a href="https://cdn.novozymes.com/sites/default/files/document/2024-09/Novonesis_Working_with_enzymes.pdf">guide</a>.

Safe handling

Product features, details and benefits

Liquid

Stereoselective hydrolysis of esters, transesterification, and esterification of acids, and acylation of amines.

Mode of action

Physical form (recyclability)

Commercial applications

Lipases

Sustine® 110 IM - Sustine® 140 - Base-1

Sustine® 140

Sustine® 140 works well in aqueous mediums, as well as in a wide range of organic solvents.

Can this product be used in both aqueous and organic solvent processes?

Sustine® 140 works well in low-water content.

Does this product work with low-water content?

Sustine® 140 is a water-soluble biocatalyst, where 2-3 aqueous extractions will remove all enzyme content.

How do I separate the enzyme from the product after reaction use?

Testing one of our products in your own production is the best way to experience all the benefits.